Is Melatonin Really Safe? New Research Raises Concerns About the Popular Sleep Aid

Is Melatonin Really Safe? New Research Raises Concerns About the Popular Sleep Aid

In recent years, melatonin supplements have become one of the most popular remedies for sleepless nights. Marketed as a “natural” solution for insomnia and jet lag, millions of people worldwide now rely on the hormone to fall asleep faster. However, new research is prompting experts to take a closer look at whether long-term use of melatonin is as safe as many believe.


A recent study highlighted by ABC7 News and Science Daily found potential links between long-term melatonin use and an increased risk of cardiovascular issues. While the research does not prove that melatonin directly causes heart problems, scientists suggest that frequent use might be a warning sign of deeper health issues—such as chronic insomnia, stress, or hormonal imbalance that need professional attention.

Doctors also warn that the unregulated nature of melatonin supplements can lead to inconsistent dosages. A 2022 study published in JAMA found that some products contained over 400% of their labeled dose, increasing the risk of side effects such as grogginess, vivid dreams, or dependency.


Experts recommend that melatonin be used only for short-term relief and in consultation with a healthcare professional. Improving sleep hygiene such as maintaining a regular bedtime, reducing screen time, and managing stress remains the most effective and safest way to achieve better sleep naturally.

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